A role for PYY3-36 in GLP1-induced insulin secretion
نویسندگان
چکیده
منابع مشابه
Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion
We previously demonstrated that the overall incretin effect and the β-cell responsiveness to glucagon-like peptide-1 (GLP1) are increased in insulin-resistant mice and may contribute to the upregulated β-cell function. Now we examined whether this could, first, be explained by increased islet GLP1 receptor (GLP1R) protein levels and, secondly, be leveraged by G-protein-coupled receptor 119 (GPR...
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Development and normal function of the reproductive axis requires a precise degree of body energy stores. Polypeptide YY3-36 (PYY3-36) is a gastrointestinal secreted molecule recently shown to be involved in the control of food intake with agonistic activity upon neuropeptide Y (NPY) receptor subtypes Y2 and Y5. Notably, PYY3-36 has been recently demonstrated as putative regulator of gonadotrop...
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ژورنال
عنوان ژورنال: Molecular Metabolism
سال: 2013
ISSN: 2212-8778
DOI: 10.1016/j.molmet.2013.06.002